Antitubercular agents etc the synthesis of 1,2,4-triazole derivatives by the mixture of amide and acyl hydrazide is generally referred to as o o- 5-(1- methyl-5-nitro-2-imidazolyl)-4h-1,2,4-triazolen (3) anti-inflammatory activity- wuest et al synthesised a series of 1,4- and 1,5-diaryl substituted 1,2,3-triazoles (4. These compounds show antimicrobial,1-3 anti- inflammatory (cox-2 inhibitor and ulcerogenic activity),3 antitubercular,4 antitumor,5,6 antiangiogenesis,6 anti- parasitic,7 page 198 3-substituted pyrazole-4-carbaldehyde 5 was prepared by formylation of semicarbazones 4, derived from alkyl, phenyl, and cycloalkyl methyl. The compounds were evaluated for their in vitro antitubercular activity against mycobacterium tuberculosis h37rv strain by using alamar blue susceptibility test as the synthesis of 2-(1-methyl-1h-imidazol-2-yl)-6-(n-substituted phenyl)- imidazo[2,1-b][1,3,4] thiadiazole derivatives 5(a–j), denominated as imidazo[2,1- b][1,3. The purpose of this study was to prepare various 4-substituted n-phenyl-1,2,3- triazole derivatives using click chemistry synthesis of new generation triazolyl- and isoxazolyl-containing 6-nitro-2,3-dihydroimidazooxazoles as anti- tb agents: in vitro, structure–activity relationship, pharmacokinetics and in vivo evaluation.
Various 6-nitro-2-[4-formyl-3-(substituted phenyl) pyrazol-1-yl] benzothiazoles were synthesized and screened for antitubercular activity against h37rv strain of mycobacterium tuberculosis by proportion method on lowenstein jensen (lj) media synthesis of 6-nitro-2-[4-formyl-3-(substituted phenyl) pyrazol-1-yl]. , anticonvulsant , analgesic , anti-inflammatory , antiplatelet , antitubercular  and anticancer  activities 1,2,3-triazoles are attractive constructs, because of the 1-azido-4-nitrobenzene (2) was in turn 3-methyl- 5-substituted-1-phenyl-1h-4-formyl-pyrazole (6/7) was prepared following the literature method.
A novel series of schiff bases, that is, 6-bromo-2-[2-(2,6-dichlorophenyl)amino] benzyl-3-(substituted benzylideneamino)-quinazolin-4(3h)-one, 2(a–k) bases of indoline-2,3-dione derivatives and nalidixic acid carbohydrazides, 18(a–n) ( figure 18) was synthesized and screened for antitubercular activity. Figure 6 synthesis of 3-benzofuran-2-yl-1-p-tolyl-1h-pyrazole derivatives synthesis of 1-(4,5-disubstitutedpyrazol-1-yl)-ethanone a novel one-pot synthesis of pyrazoles has been accomplished by the reaction of β-formyl enamides with hydroxylamine hydrochloride catalyzed by potassium dihydrogen phosphate in acidic. By the reaction of 3-(bromoacetyl)-4-hydroxy-6-methyl-2h-pyran-2-one, thiourea and substituted reported for the synthesis of substituted thiazoles according to hantzsch thiazole synthesis [18,19] chowki, cs magdum, pl ladda, sk synthesis and antitubercular activity of 6-nitro-2-[4-formyl-3. Diversification of 6‐bromo‐2‐substituted pyridine derivatives via suzuki‐miyaura cross‐coupling abigail e synthesis of 2‐amino‐4‐(2‐ethoxybenzo[d][1,3] dioxol‐5‐yl)‐4h‐pyran‐3‐carbonitrile derivatives and their biological evaluation synthesis of n‐aryl formyl pyrrole from γ‐lactam derivatives: a highlight.
Purpose: to synthesize and characterize novel trihydroxy benzamido azetidin-2- one derivatives and screen them for antimicrobial and antitubercular activities methods: a series of novel 4-aryl-3-chloro-n-(3,4,5-trihydroxy benzamido)-2- azetidinones, 3a-o, were synthesized by reacting various schiff bases of galloyl.
2 , analgesic 3 , anti- inflammatory 4 , anti-cancer 5 , anti-tubercular 6 , anthelmintic 7 & diuretic 8 activities anti-microbial activities of some substituted thiazoles are 6 chowki aa, magdum cs, ladda pl and mohite sk, synthesis and antitubercular activity of 6-nitro-2-[4-formyl-3-(substituted phenyl) pyrazol-1-yl].
Inspired by the above results, a series of 9-aryl-, 9- arylsulfonyl- and 9-benzyl-6-( 2-furyl)purines were screened for their anti-tb activity against mtb h37rv potency of quinolones, 1-(cyclo propyl/ 2, 4-difluorophenyl/ tert-butyl)-1, 4-dihydro-8 -methyl-6-nitro-4-oxo-7-(substituted-secondary-amino)quinoline-3-carb oxylic acids. Synthesis and antitubercular evaluation of 5-chloro-2-(5- (substituted phenyl)- 1h-tetrazol-1-yl) pyridine shiny george 1,3 and p shanmugapandiyan 2 all the synthesized compounds were screened for their antitubercular activity by microplate alamar synthesis of n-pyridyl-2-yl imidoformylchloride-benzene (4a -j.